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preLights peer support – preprints of interest

This is a preprint repository to organise the preprints and preLights covered through the 'preLights peer support' initiative.

List by preLights peer support

Preprints:

How to reach out to contribute (either to suggest preprints OR to write a preLight)?
preLighters:slack DMs
others:email to girish.kale [at] cos.uni-heidelberg.de OR use theContactform above. In either case, please add ‘preLights peer support’ in the subject line.

What all information is available in this preList?
This preList contains various details about interesting preprints. The preprints are typically associated with apreLighter, who is willing to play the role of “editor” (for the time being,Girish Kaleis the ‘default’ preLighter). When someone has already reached out to highlight a preprint, the name of thewriter将出现在预印本描述(如果这我吗s (you?), the preprint is still ‘up for grabs’). Each preprint will also carry a bunch ofkeywords: these could be from the preprint itself, or additional ones based on a quick reading of the manuscript. Additionally, if the preprint is already highlighted, then a link to thepreLightpost will appear below. Once themanuscript is published, there will be a link to the published version of records (naturally, these preprints can’t be highlighted anymore).

How is the preList page organised?
The preprints are sorted reverse-chronologically (latest preprints on the top). Ideally, the preprints at the top should be preferred over the older ones, though, if you find an older preprint to be really interesting, feel free to reach out to check if it can still be added to the preList, or highlighted if already in the preList. Keep in mind that, sooner or later the old preprints will be published, and can’t be highlighted through preLights anymore.

2023 October

A morphogenic cascade emerges from the co-evolution of spheroid fluidization and fracturing of multicellular barriers

Selwin Kaixiang Wu, Celestine Z. Ho, Fuqiang Sun,Yuting Lou, Christina Bao-Xian Huang,Jingwei Xiao,Murat Shagirov,Ivan Yow,Jasmine Fei Li Chin,Suzie Verma,Alpha Yap,Yuan Lin,Tetsuya Hiraiwa,Boon Chuan Low

https://www.biorxiv.org/content/10.1101/2023.09.25.559247v2

preLighter:(default)

writer:(you?)

keywords:Cell biology, solid-to-fluid-like transition, cancer spheroid invading mesothelium, tissue fracture and fluidisation, 3D cell culture

preLight:(not yet highlighted)

manuscript is published:(not yet)

Temporal restriction of RNAi reveals breakdown of the segmentation clock is reversible after knock down of primary pair rule genes but not Wnt-signaling in the red flour beetle

Felix Kaufholz, Julia C Ulrich, Muhammad S Hakeemi,Gregor Bucher

https://www.biorxiv.org/content/10.1101/2023.10.15.562380v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, Embryogenesis, Insect segmentation, clock and wavefront/speed gradient model, segmentation breakdown, RNAi, transgenic tool, red flour beetle

preLight:(not yet highlighted)

manuscript is published:(not yet)

Adaptive genomic variation is linked to a climatic gradient in a social wasp

Hannah L Cook,Sara E Miller,Gilbert Giri,Kevin J Loope,Michael J Sheehan,Floria M.K. Uy

https://www.biorxiv.org/content/10.1101/2023.10.12.561994v1

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, climatic gradient, genomic variation, genotype-environment associations, local adaptation, Mischocyttarus mexicanus, social wasp

preLight:(not yet highlighted)

manuscript is published:(not yet)

Tropical high-altitude insects show limited capacity to handle high temperatures

Harshad Vijay Mayekar, Pooran Singh Solanki, Homica Arya, Rajaguru Aradhya, Prashanth Suravajhala, Volker Loeschcke,Subhash Rajpurohit

https://www.biorxiv.org/content/10.1101/2022.09.10.507406v2

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, Heat, Climate change, Rapid adaptation, High altitudes,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

Scale-independent topological interactions drive the first fate decision in the Drosophila embryo

Woonyung Hur,Arghyadip Mukherjee,Luke Hayden,Ziqi Lu, Anna Chao,Noah P. Mitchell,Sebastian J. Streichan,Massimo Vergassola,Stefano Di Talia

https://www.biorxiv.org/content/10.1101/2023.10.11.561879v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, Embryogenesis, Spindle orientation, Nuclear fate, Microtubule structures, Cell fate determination,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

Vinculin Antagonizes Branched Actin in Controlling Membrane Protrusion, Cell Migration and Cell Cycle Progression

John James,Artem I. Fokin,Dmitry Y. Guschin,Hong Wang,Anna Polesskaya,Svetlana N. Rubtsova,Christophe Le Clainche,Pascal Silberzan,Alexis M. Gautreau,Stéphane Romero

https://www.biorxiv.org/content/10.1101/2023.10.09.561480v1

preLighter:(default)

writer:(you?)

keywords:Cell biology, Vinculin, Mechanotransducer, Cell adhesions, Arp2/3, Actin networks, Migration, Cell-cell junctions

preLight:(not yet highlighted)

manuscript is published:(not yet)

Hibernating ribosomes tether to mitochondria as an adaptive response to cellular stress during glucose depletion

Olivier Gemin, Maciej Gluc, Michael Purdy, Higor Rosa, Moritz Niemann, Yelena Peskova,Simone Mattei,Ahmad Jomaa

https://www.biorxiv.org/content/10.1101/2023.10.08.561365v1

preLighter:(default)

writer:(you?)

keywords:Molecular biology, Nutrient deprivation, Ribosomal sequestration, Mitochondrial fragmentation, Protein synthesis, Cellular adaptation

preLight:(not yet highlighted)

manuscript is published:(not yet)

Visualisation of gene expression within the context of tissues: an X-ray computed tomography-based multimodal approach

Kristaps Kairiss,Natalia Sokolova,Lucie Zilova,Christina Schlagheck,Robert Reinhardt,Tilo Baumbach, Tomas Farago,Thomas van de Kamp,Joachim Wittbrodt,Venera Weinhardt

https://www.biorxiv.org/content/10.1101/2023.10.09.561491v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, multimodal labelling, X-ray computed-tomography, light sheet microscopy,in situhybridisation, immunofluorescence, rice fish (medaka), organoids

preLight:(not yet highlighted)

manuscript is published:(not yet)

Quantitative proteome dynamics across embryogenesis in a model chordate

Alexander N. Frese,Andrea Mariossi,Michael S. Levine,Martin Wühr

https://www.biorxiv.org/content/10.1101/2023.10.04.559613v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, Evolution, gene expression programs, vertebrates, proteome atlas, developmental stages, multi-omics analysis, Transcriptome, Chordates, Vertebrates, Ciona, Xenopus

preLight:(not yet highlighted)

manuscript is published:(not yet)

Segmentation in tapeworms as a modified form of flatworm posterior regeneration involving Wnt and Hedgehog signalling

Francesca Jarero,Andrew Baillie,Nick Riddiford, Jimena Montagne,Uriel Koziol,Peter D Olson

https://www.biorxiv.org/content/10.1101/2023.10.02.560491v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, segmentation, anteroposterior patterning, regeneration, tapeworm, Wnt, Hedgehog

preLight:(not yet highlighted)

manuscript is published:(not yet)

2023 September

Local Thermal Adaptation occurs via Modulation of Mitochondrial Activity in Chinook Salmon

Bradford A Dimos, Alex C Lopez, Patricia M. Schulte, Michael P Phelps

https://www.biorxiv.org/content/10.1101/2023.09.28.560008v1

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, Thermal Adaptation, Mitochondria, metabolism, non-model species

preLight:(not yet highlighted)

manuscript is published:(not yet)

Open top multi sample dual view light sheet microscope for live imaging of large multicellular systems

Franziska Moos,Simon Suppinger,Gustavo de Medeiros,Koen Oost, Andrea Boni, Camille Remy,Sera Weevers,Charisios D Tsiairis, Petr Strnad,Prisca Liberali

https://www.biorxiv.org/content/10.1101/2023.09.28.559925v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, light sheet microscopy, high content microscopy, intestinal organoids, gastruloids, live imaging, new imaging techniques

preLight:(not yet highlighted)

manuscript is published:(not yet)

Myocardin-related transcription factors regulate morphogenetic events in vertebrate embryos by controlling F-actin organization and apical constriction

Keiji Itoh,Olga Ossipova,Miho Matsuda,Sergei Y Sokol

https://www.biorxiv.org/content/10.1101/2023.09.27.559818v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, Mrtf, serum response factor, morphogenesis, gastrulation, megakaryoblastic leukemia, Mkl, F-actin, Xenopus embryo, apical constriction, blastopore, neural tube closure, tricellular junctions

preLight:(not yet highlighted)

manuscript is published:(not yet)

Notch signalling plays a critical role in patterning the ventral mesoderm during early embryogenesis in Drosophila melanogaster

Marvel Megaly, Gregory Foran, Arsala Ali, Anel Turgambayeva, Ryan D. Hallam, Aleksandar Necakov

https://www.biorxiv.org/content/10.1101/2023.09.27.558900v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, Notch signalling,Drosophila, mesoderm, morphogenesis, dorso-ventral patterning

preLight:(not yet highlighted)

manuscript is published:(not yet)

Transcriptome analysis reveals temporally regulated genetic networks during Drosophila border cell collective migration

Emily Burghardt,Jessica Rakijas,Antariksh Tyagi,Pralay Majumder,Bradley J.S.C. Olson,Jocelyn A. McDonald

https://www.biorxiv.org/content/10.1101/2023.09.27.559830v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, Collective cell migration, oogenesis, adhesion, morphogenesis, ribosome, RNA-seq,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

Cell proliferation and Notch signaling coordinate the formation of epithelial folds in the Drosophila leg

Alonso Rodriguez, Sergio Cordoba, Daniel Delipe-Cordero, Antonio Baonza,David Miguez,Carlos Estella

https://www.biorxiv.org/content/10.1101/2023.09.28.559944v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, Notch signalling, cell proliferation, morphogenesis, epithelia,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

Embryogenesis in myrmicine ants combines features of short and long germ-band modes of development

Chi-Chun Fang,Arjuna Rajakumar,Andrew Kenny,Ulrich G. Mueller,Ehab Abouheif,David Stein

https://www.biorxiv.org/content/10.1101/2023.09.19.557849v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, morphogenesis, embryogenesis, segmental patterning, development in non-model organisms, ant species, Hymenoptera

preLight:(not yet highlighted)

manuscript is published:(not yet)

Sensitivity of the timing ofDrosophilapupal wing morphogenesis to external perturbations

Romina Piscitello-Gómez, Ali Mahmoud,Natalie A Dye, Suzanne Eaton

https://www.biorxiv.org/content/10.1101/2023.09.22.558969v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, morphogenesis,Drosophila, pupal wing

preLight:(not yet highlighted)

manuscript is published:(not yet)

Strong environmental memory revealed by experimental evolution in static and fluctuating environments

Clare I. Abreu, Shaili Mathur, Dmitri A. Petrov

https://www.biorxiv.org/content/10.1101/2023.09.14.557739v2

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, laboratory evolution, barcoded yeast lineages, non-additive effects, environmental memory

preLight:(not yet highlighted)

manuscript is published:(not yet)

GC content across insect genomes: phylogenetic patterns, causes and consequences

Riccardo G. Kyriacou,Peter O. Mulhair,Peter W. H. Holland

https://www.biorxiv.org/content/10.1101/2023.09.11.557135v1

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, GC content, phylogenetic patterns, genome biology, coding region

preLight:(not yet highlighted)

manuscript is published:(not yet)

An actomyosin network organizes niche morphology and responds to feedback from recruited stem cells

Bailey N. Warder,Kara A. Nelson, Justin Sui,Lauren Anllo,Stephen DiNardo

https://www.biorxiv.org/content/10.1101/2023.09.08.556877v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, morphogenesis,Drosophila, actomyosin networks, stem cells to niche feedback

preLight:(not yet highlighted)

manuscript is published:(not yet)

Conserved nucleocytoplasmic density homeostasis drives cellular organization across eukaryotes

Abin Biswas, Omar Muñoz,Kyoohyun Kim, Carsten Hoege,Benjamin M. Lorton,David Shechter,Jochen Guck,Vasily Zaburdaev,Simone Reber

https://www.biorxiv.org/content/10.1101/2023.09.05.556409v1

preLighter:(default)

writer:(you?)

keywords:Biophysics, nucleoplasm and cytoplasm density, nuclear-to-cytoplasmic ratio,C. elegans, label-free biophotonics, theory

preLight:(not yet highlighted)

manuscript is published:(not yet)

Vinculin is Essential For Sustaining Normal Levels of Endogenous Force Transmission at Cell-Cell Contacts

Mazen Mezher, Sandeep Dumbali, Ian Fenn, Carter Lamb, Conrad Miller, Jolene I. Cabe, Vidal Bejar-Padilla, Daniel Conway, Venkat Maruthamuthu

https://www.biorxiv.org/content/10.1101/2023.09.05.556369v1

preLighter:(default)

writer:(you?)

keywords:Biophysics, E-cadherin, α-catenin, vinculin, force transmission, adhesion strength

preLight:(not yet highlighted)

manuscript is published:(not yet)

Genetic basis of variation in thermal developmental plasticity forDrosophila melanogasterbody pigmentation

E Lafuente,D Duneau,P Beldade

https://www.biorxiv.org/content/10.1101/2023.09.03.556093v1

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, developmental plasticity; thermal melanism; insect coloration; Genome-Wide Association Study (GWAS);DrosophilaGenetic Reference Panel (DGRP); seasonal variation

preLight:(not yet highlighted)

manuscript is published:(not yet)

Mechanosensing through talin 1 contributes to tissue mechanical homeostasis

Manasa V.L. Chanduri,Abhishek Kumar,Dar Weiss, Nir Emuna,Igor Barsukov, Muisi Shi,Keiichiro Tanaka, Xinzhe Wang,Amit Datye,Jean Kanyo, Florine Collin,TuKiet Lam,Udo D. Schwarz, Suxia Bai,Timothy Nottoli,Benjamin T Goult,Jay D. Humphrey,Martin A Schwartz

https://www.biorxiv.org/content/10.1101/2023.09.03.556084v1

preLighter:(default)

writer:(you?)

keywords:Cell biology, mechanosensing, tissue mechanical homeostasis, talin, cell-ECM interactions

preLight:(not yet highlighted)

manuscript is published:(not yet)

2023 August

Immigration delays but does not prevent adaptation following environmental change: experimental evidence

Lily F. Durkee,Laure Olazcuaga,Brett A. Melbourne,Ruth A. Hufbauer

https://www.biorxiv.org/content/10.1101/2023.08.31.555763v1

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, natural selection, evolutionary rescue, dispersal,种有害castaneum, gene flow, translocation

preLight:(not yet highlighted)

manuscript is published:(not yet)

Modular control of time and space during vertebrate axis segmentation

Ali Seleit,Ian Brettell,Tomas Fitzgerald,Carina Vibe,Felix Loosli,Joachim Wittbrodt,Kiyoshi Naruse,Ewan Birney,Alexander Aulehla

https://www.biorxiv.org/content/10.1101/2023.08.30.555457v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, rice fish (medaka), segmentation tempo, developmental time, developmental constraints, QTL, CRISPR/Cas9, genetic hybridization, scaling

preLight:(not yet highlighted)

manuscript is published:(not yet)

Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension

Jianbo Wang, Chenbei Chang, Hwa-seon Seo, Deli Yu, Ivan Popov, Jiahui Tao, Allyson Angermeier, Bingdong Sha,Jeffrey D. Axelrod

https://www.biorxiv.org/content/10.1101/2023.08.29.555374v2

preLighter:(default)

writer:(you?)

keywords:Developmental biology, convergent extension, planar cell polarity, non-canonical wnt signalling,Xenopusembryos

preLight:(not yet highlighted)

manuscript is published:(not yet)

Insights into Digit Evolution from a Fate Map Study of the Forearm

JDH Oh,DDZ Saunders, L McTeir, M Jackson,JD Glover,JJ Schoenebeck,LA Lettice,MG Davey

https://www.biorxiv.org/content/10.1101/2023.08.29.555165v2

preLighter:(default)

writer:(you?)

keywords:Developmental biology, digit evolution, morphogenesis, chicken embryos

preLight:(not yet highlighted)

manuscript is published:(not yet)

Morphogen gradients can convey position and time in growing tissues

罗马检查者,Dagmar Iber

https://www.biorxiv.org/content/10.1101/2023.08.28.555133v2

preLighter:(default)

writer:(you?)

keywords:Developmental biology, tissue patterning, morphogen gradient, time, opposing gradients, neural tube, Sonic hedgehog

preLight:(not yet highlighted)

manuscript is published:(not yet)

Morphodynamics of human early brain organoid development

Akanksha Jain,Gilles Gut,Fátima Sanchis-Calleja,Ryoko Okamoto, Simon Streib,Zhisong He,Fides Zenk, Malgorzata Santel,Makiko Seimiya, René Holtackers,Sophie Martina Johanna Jansen,J. Gray Camp,Barbara Treutlein

https://www.biorxiv.org/content/10.1101/2023.08.21.553827v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, brain organoid, light sheet microscopy, single-cell transcriptome, mechanosensing

preLight:(not yet highlighted)

manuscript is published:(not yet)

Nucleotide sharing through gap junctions buffers replication stress

Benjamin Boumard, Gwenn Le Meur, Tania Maalouf, Marwa El-Hajj, Reinhard Bauer,Allison J. Bardin

https://www.biorxiv.org/content/10.1101/2023.08.15.553366v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, gap junctions, metabolism, replication stress, stem cells

preLight:(not yet highlighted)

manuscript is published:(not yet)

Successful regeneration of the adult zebrafish retina is dependent on inflammatory signaling

Oliver Bludau, Anke Weber, Viktoria Bosak, Veronika Kuscha, Kristin Dietrich,Stefan Hans,Michael Brand

https://www.biorxiv.org/content/10.1101/2023.08.11.552956v2

preLighter:(default)

writer:(you?)

keywords:发育生物学、免疫抑制、csf,microglia, Müller glia, NF-κB pathway, retina regeneration, zebrafish

preLight:(not yet highlighted)

manuscript is published:(not yet)

Transcriptional control of compartmental boundary positioning during Drosophila wing development

Gustavo Aguilar, Michèle Sickmann, Dimitri Bieli, Gordian Born,Markus Affolter,Martin Müller

https://www.biorxiv.org/content/10.1101/2023.08.05.552106v2

preLighter:(default)

writer:(you?)

keywords:Developmental biology, Enhancer, CRISPR, HOX, Antennapedia, apterous, wing disc, dCas, dCRISPR, GATA

preLight:(not yet highlighted)

manuscript is published:(not yet)

The cell adhesion molecule Echinoid promotes tissue survival and separately restricts tissue overgrowth inDrosophilaimaginal discs

Danielle C. Spitzer, William Y. Sun,安东尼Rodriguez-Vargas,Iswar K. Hariharan

https://www.biorxiv.org/content/10.1101/2023.08.04.552072v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, echinoid, hippo-pathway, tissue growth regulation, Drosophila imaginal discs

preLight:(not yet highlighted)

manuscript is published:(not yet)

Investigating the phylogenetic history of toxin tolerance in mushroom-feedingDrosophila

Theresa Erlenbach, Lauren Haynes, Olivia Fish, Jordan Beveridge, Eunice Bingolo, Sarah-Ashley Giambrone, Grace Kropelin, Stephanie Rudisill, Pablo Chialvo, Laura K. Reed, Kelly A. Dyer, Clare Scott Chialvo

https://www.biorxiv.org/content/10.1101/2023.08.03.551872v1

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, Ancestral state reconstruction, Amanita mushrooms, phylogenetics, mycophagy, biochemical novelty, toxin tolerance

preLight:(not yet highlighted)

manuscript is published:(not yet)

Scaling between cell cycle duration and wing growth is regulated by Fat-Dachsous signaling inDrosophila

Andrew Liu, Jessica O’Connell, Farley Wall,Richard W. Carthew

https://www.biorxiv.org/content/10.1101/2023.08.01.551465v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, Fat-Dachsous, hippo-pathway, tissue growth regulation, Drosophila wing

preLight:(not yet highlighted)

manuscript is published:(not yet)

Conserved and novel enhancers regulate expression ofAedes aegypti single-mindedin the embryonic ventral midline

Isabella Schember, William Reid,Marc S. Halfon

https://www.biorxiv.org/content/10.1101/2023.08.01.551414v1

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, enhancer evolution,single minded, nervous system master regulator, embryo development,Aedes aegypti,Drosophila melanogaster,

preLight:(not yet highlighted)

manuscript is published:(not yet)

2023 July

Global decoupling of cell differentiation from cell division in early embryo development

Kalki Kukreja, Nikit Patel, Sean G Megason, Allon M Klein

https://www.biorxiv.org/content/10.1101/2023.07.29.551123v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, cell division, cell differentiation, embryo development, single-cell RNAseq, zebrafish

preLight:(not yet highlighted)

manuscript is published:(not yet)

α-Catenin Dependent E-cadherin Adhesion Dynamics as Revealed by an Accelerated Force Ramp

Joshua Bush, Jolene I. Cabe,Daniel Conway, Venkat Maruthamuthu

https://www.biorxiv.org/content/10.1101/2023.07.28.550975v2

manuscript is published:https://doi.org/10.1016/j.bbrc.2023.09.077

Growth directions and stiffness across cell layers determine whether tissues stay smooth or buckle

Avilash S. Yadav,Lilan Hong,Patrick M. Klees,Annamaria Kiss,Xi He,Iselle M. Barrios,Michelle Heeney,Anabella Maria D. Galang,Richard S. Smith,Arezki Boudaoud,Adrienne H.K. Roeder

https://www.biorxiv.org/content/10.1101/2023.07.22.549953v2

preLighter:(default)

writer:(you?)

keywords:Developmental biology, tissue growth regulation, tissue interactions, growth direction, tissue stiffness,Arabidopsis

preLight:(not yet highlighted)

manuscript is published:(not yet)

BMP-dependent patterning of ectoderm tissue material properties modulates lateral mesendoderm cell migration during early zebrafish gastrulation

Stefania Tavano,David B. Brückner, Saren Tasciyan, Xin Tong, Roland Kardos, Alexandra Schauer, Robert Hauschild, Carl-Philipp Heisenberg

https://www.biorxiv.org/content/10.1101/2023.07.21.550024v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, gastrulation, tissue material properties, embryo development, zebrafish

preLight:(not yet highlighted)

manuscript is published:(not yet)

Cell division angle regulates the tissue mechanics and tunes the amount of cerebellar folding

Amber G. Cook, Taylor V. Bishop,Hannah R. Crowe, Daniel Stevens, Lauren Reine,Alexandra L Joyner,Andrew K Lawton

https://www.biorxiv.org/content/10.1101/2023.07.21.549165v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, cerebellum, brain folding, cell division angle, tissue mechanics, mouse models

preLight:(not yet highlighted)

manuscript is published:(not yet)

Ran-GTP assembles a specialized spindle structure for accurate chromosome segregation in medaka early embryos

Ai Kiyomitsu, Toshiya Nishimura, Shiang Jyi Hwang, Satoshi Ansai,Masato T. Kanemaki, Minoru Tanaka,Tomomi Kiyomitsu

https://www.biorxiv.org/content/10.1101/2023.07.20.549960v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, mitotic spindle, chromosome segregation defects, CRISPR knock-in, rice fish (medaka)

preLight:(not yet highlighted)

manuscript is published:(not yet)

Coordination of cell cycle and morphogenesis during organ formation

Jeffrey Matthew,Vishakha Vishwakarma,Thao Phuong Le, Ryan A. Agsunod,SeYeon Chung

https://www.biorxiv.org/content/10.1101/2023.07.20.549944v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, salivary gland, Huckebein, endoreplication, endocycle, apoptosis, epithelial tube formation,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

Drosophilaaxis extension is robust to an orthogonal pull by invaginating mesoderm

Claire M Lye,Guy B. Blanchard,Jenny Evans,Alexander Nestor-Bergmann,Bénédicte Sanson

https://www.biorxiv.org/content/10.1101/2023.07.18.549479v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, Mechanical interactions; germband extension; actomyosin cortex; planar polarity; cell neighbour exchanges; convergent extension; live imaging; cell tracking; gastrulation,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

Amphibian segmentation clock models suggest mechanisms of slowed development across increasing genome size and nuclear volume

Alexandra Nicole Taylor, Rachel Lockridge Mueller,Ashok Prasad

https://www.biorxiv.org/content/10.1101/2023.07.16.549220v2

preLighter:(default)

writer:(you?)

keywords:Developmental biology, Somitogenesis, cell size, genomic expansion, intron delay, gene expression kinetics, nucleoplasmic diffusion,Xenopus laevisandAmbystoma mexicanum

preLight:(not yet highlighted)

manuscript is published:(not yet)

Evolution of compound eye morphology underlies differences in vision between closely relatedDrosophilaspecies

Alexandra D Buffry,John P Currea,Franziska A Franke,Ravindra Palavalli-Nettimi, Andrew J Bodey, Christoph Rau, Nazanin Samadi,Stefan J Gstöhl,Christian M Schlepütz,Alistair P McGregor,Lauren Sumner-Rooney,Jamie Theobald,Maike Kittelmann

https://www.biorxiv.org/content/10.1101/2023.07.16.549164v1

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, eye structure and vision, 3D synchrotron radiation tomography, optomotor response tracking,Drosophila mauritianaandsimulans

preLight:(not yet highlighted)

manuscript is published:(not yet)

Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells

Nadia M.E. Ayad, Johnathon N. Lakins, Ajinkya Ghagre,Allen J. Ehrlicher, Valerie M. Weaver

https://www.biorxiv.org/content/10.1101/2023.07.14.549074v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, gastrulation, mechanical forces, β-catenin, mesoderm specification, Wnt signaling, human embryonic stem cells, cytoskeletal tension, mechanotransduction, gastruloids, traction force microscopy (TFM)

preLight:(not yet highlighted)

manuscript is published:(not yet)

The scorpionfly (Panorpa cognata) genome highlights conserved and derived features of the peculiar dipteran X chromosome

Clementine Lasne,Marwan Elkrewi,Melissa A. Toups,Lorena Layana, Ariana Macon,Beatriz Vicoso

https://www.biorxiv.org/content/10.1101/2023.07.11.548499v1

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, insects, sex-chromosome evolution, Muller element F, scorpionfliesPanorpa cognata

preLight:(not yet highlighted)

manuscript is published:(not yet)

Naturally segregating genetic variants contribute to thermal tolerance in aD. melanogaster model system

Patricka A. Williams-Simon, Camille Oster, Jordyn A. Moaton, Ronel Ghidey,Enoch Ng’oma,Kevin M. Middleton, Troy Zars,Elizabeth G. King

https://www.biorxiv.org/content/10.1101/2023.07.06.547110v1

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, QTL, Thermal Tolerance, DSPR, RNA-seq, Gene Expression, RNAi, Complex Traits,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

2023 June

Cracked actin filaments as mechanosensitive receptors

Vilmos Zsolnay, Margaret L. Gardel, David R. Kovar, Gregory A. Voth

https://www.biorxiv.org/content/10.1101/2023.06.26.546553v1

preLighter:(default)

writer:(you?)

keywords:生物物理学、分子动力学模拟,F-actin filaments under tensile strain

preLight:(not yet highlighted)

manuscript is published:(not yet)

Patterning and folding of intestinal villi by active mesenchymal dewetting

Tyler R. Huycke, Hikaru Miyazaki, Teemu J. Häkkinen, Vasudha Srivastava, Emilie Barruet, Christopher S. McGinnis, Ali Kalantari, Jake Cornwall-Scoones, Dedeepya Vaka, Qin Zhu, Hyunil Jo, William F. DeGrado, Matt Thomson, Krishna Garikipati, Dario Boffelli, Ophir D. Klein, Zev J. Gartner

https://www.biorxiv.org/content/10.1101/2023.06.25.546328v2

preLighter:(default)

writer:(you?)

keywords:Developmental biology, tissue folding, intestinal epithelium, tissue interactions, single-cell RNAseq, mouse model

preLight:(not yet highlighted)

manuscript is published:(not yet)

A cytokinetic ring-driven cell rotation achieves Hertwig’s rule in early development

Teije C. Middelkoop,乔纳斯Neipel,凯特琳·e·康奈尔,罗依nald Naumann,Lokesh g . PimpaleFrank Jülicher,Stephan W. Grill

https://www.biorxiv.org/content/10.1101/2023.06.23.546115v2

preLighter:(default)

writer:(you?)

keywords:Developmental biology, cell division, theoretical model, actomyosin contractility,C. elegans

preLight:(not yet highlighted)

manuscript is published:(not yet)

Evolution of Plasticity in Response to Ethanol between Recently Separated Populations ofD. melanogaster与不同的生态历史

George Boateng-Sarfo, Franz Scherping, Murad Mammadov, Sarah Signor

https://www.biorxiv.org/content/10.1101/2023.06.22.546145v1

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, phenotypic plasticity, ethanol metabolism, adaptation,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

2023 May

Distinctive cellular and junctional dynamics independently regulate the rotation and elongation of the internal organ

Mikiko Inaki, Takamasa Higashi, Satoru Okuda, Kenji Matsuno

https://www.biorxiv.org/content/10.1101/2023.05.22.541825v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, chiral cell-sliding, cell-intercalation, gut tube rotation, left-right asymmetry,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

Apical-driven cell sorting optimised for tissue geometry ensures robust patterning

https://www.biorxiv.org/content/10.1101/2023.05.16.540918v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, fate segregation, cell mechanics, cell sorting, cell migration, apical polarity, extracellular matrix, tissue geometry, embryo patterning, robustness, morphogenesis

preLight:(not yet highlighted)

manuscript is published:(not yet)

Dissecting genetic correlation through recombinant perturbations: the role of developmental bias

Haoran Cai,Kerry Geiler-Samerotte,David L. Des Marais

https://www.biorxiv.org/content/10.1101/2023.05.12.540583v4

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, Genetics, Pleiotropy; Genetic correlation; Developmental bias; Evolvability

preLight:(not yet highlighted)

manuscript is published:(not yet)

Regeneration from three cellular sources and ectopic mini-retina formation upon neurotoxic retinal degeneration inXenopus

Parain Karine, Albert Chesneau, Morgane Locker, Caroline Borday, Perron Muriel

https://www.biorxiv.org/content/10.1101/2023.05.12.540545v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, retina, photoreceptor degeneration, cobalt chloride, regeneration, Müller glia, ciliary marginal zone, retinal pigmented epithelium,Xenopus laevis,Xenopus tropicalis

preLight:(not yet highlighted)

manuscript is published:(not yet)

Hypoxia delays steroid-induced developmental maturation inDrosophilaby suppressing EGF signaling

Michael J Turingan, Tan Li, Jenna Wright, Savraj S Grewal

https://www.biorxiv.org/content/10.1101/2023.05.12.540517v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, development in hypoxia, ecdysone signalling, EGFR signalling,Drosophilalarvae

preLight:(not yet highlighted)

manuscript is published:(not yet)

Inverse blebs operate as hydraulic pumps during mouse blastocyst formation

Markus F. Schliffka, Julien G. Dumortier, Diane Pelzer, Arghyadip Mukherjee,Jean-Léon Maître

https://www.biorxiv.org/content/10.1101/2023.05.03.539105v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, lumen formation, fluid pressure, cell adhesion, mouse embryos

preLight:(not yet highlighted)

manuscript is published:(not yet)

Mechanical regulation of substrate adhesion and de-adhesion drives a cell contractile wave during tissue morphogenesis

Claudio Collinet, Anaïs Bailles,Thomas Lecuit

https://www.biorxiv.org/content/10.1101/2023.05.02.539070v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, gastrulation, morphogenesis, mechanical feedback,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

2023 April

TheDrosophila drop-deadgene is required for eggshell integrity

Tayler D. Sheahan, Amanpreet Grewal, Laura E. Korthauer,Edward M. Blumenthal

https://www.biorxiv.org/content/10.1101/2023.04.25.538335v2

preLighter:(default)

writer:(you?)

keywords:Developmental biology, oogenesis, vitelline membrane biogenesis,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

RhoA GEF Mcf2lb regulates rosette integrity during collective cell migration

Hannah M. Olson, Amanda Maxfield,Nicholas L. Calistri, Laura M. Heiser,Alex V. Nechiporuk

https://www.biorxiv.org/content/10.1101/2023.04.19.537573v2

preLighter:(default)

writer:(you?)

keywords:Developmental biology, collective cell migration, posterior lateral line, cell contractility, zebrafish

preLight:(not yet highlighted)

manuscript is published:(not yet)

Bitesize bundles F-actin and influences actin remodeling in syncytialDrosophilaembryo development

Anna R. Yeh, Gregory J. Hoeprich, Bruce L. Goode, Adam C. Martin

https://www.biorxiv.org/content/10.1101/2023.04.17.537198v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, syncytial divisions, F-actin regulation,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

Evolutionarily conserved role of serotonin signaling in regulating actomyosin contractility during morphogenesis

Sanjay Karki,Mehdi Saadaoui,Valentin Dunsing, Elise Da Silva, Jean-Marc Philippe,Cédric Maurange,Thomas Lecuit

https://www.biorxiv.org/content/10.1101/2023.04.12.535044v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, serotonin signalling, actomyosin contractility regulation, GPCR signalling, gastrulation, Fly and Chicken embryos

preLight:(not yet highlighted)

manuscript is published:(not yet)

Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts

Feyza Nur Arslan,Édouard Hannezo,Jack Merrin,Martin Loose,Carl-Philipp Heisenberg

https://www.biorxiv.org/content/10.1101/2023.04.11.536411v1

preLighter:(default)

writer:(you?)

keywords:细胞生物学、细胞粘附、肌动球蛋白的监管, biomimetic assay

preLight:(not yet highlighted)

manuscript is published:(not yet)

2023 March

The positioning mechanics of microtubule asters inDrosophilaembryo explants

Jorge de-Carvalho,Sham Tlili,Timothy E. Saunders,Ivo A. Telley

https://www.biorxiv.org/content/10.1101/2023.03.31.535028v2

preLighter:(default)

writer:(you?)

keywords:Biophysics, Centrosome, cytoskeleton, ex vivo, microtubules, active systems

preLight:(not yet highlighted)

manuscript is published:(not yet)

Mitochondrial morphology dynamics and ROS regulate apical polarity and differentiation inDrosophilafollicle cells

Bhavin Uttekar,Darshika Tomer,Richa Rikhy

https://www.biorxiv.org/content/10.1101/2023.03.10.532033v1

preLighter:(default)

writer:(you?)

keywords:Developmental biology, epithelial polarity, mitochondria, ROS, aPKC, Drp1, Opa1,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

2023 February

Desmosome-anchored intermediate filaments facilitate tension-sensitive RhoA signaling for epithelial homeostasis

Bageshri Naimish Nanavati,Ivar Noordstra, Suzie Verma, Kinga Duszyc, Kathleen J. Green, Alpha S. Yap

https://www.biorxiv.org/content/10.1101/2023.02.23.529786v1

preLighter:(default)

writer:(you?)

keywords:Cell biology, Epithelia, Mechanotransduction, Desmoplakin, Intermediate Filaments, RhoA

preLight:(not yet highlighted)

manuscript is published:(not yet)

Geographic variation of theforgene reveals signatures of local adaptation inDrosophila melanogaster

Dylan J. Padilla Perez

https://www.biorxiv.org/content/10.1101/2023.02.19.529142v3

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, foraging mode, landscape genetics, polymorphism, heterogeneous environments, path length,Drosophila

preLight:(not yet highlighted)

manuscript is published:(not yet)

Planarians employ diverse and dynamic stem cell microenvironments to support whole-body regeneration

Blair W. Benham-Pyle,Frederick G. Mann Jr.,Carolyn E. Brewster,Enya R. Dewars, Dung M. Vuu,Stephanie H. Nowotarski, Carlos Guerrero-Hernández,Seth Malloy, Kate E. Hall,Lucinda E. Maddera,Shiyuan Chen,Jason A. Morrison,Sean A. McKinney,Brian D. Slaughter,Anoja Perera,Alejandro Sánchez Alvarado

https://www.biorxiv.org/content/10.1101/2022.03.20.485025v4

preLighter:Girish Kale (profile)

writer:Rebecca Kern

keywords:Developmental biology, planarians, regeneration, slide-seqv2, stem cell niche

preLight:When it comes to planarian stem cells, it’s not a one-niche-fits-all situation.

manuscript is published:?

2023 January

CartoCell, a high-content pipeline for 3D image analysis, unveils cell morphology patterns in epithelia

Jesús A. Andrés-San Román,Carmen Gordillo-Vázquez,Daniel Franco-Barranco,Laura Morato,Cecilia H. Fernández-Espartero, Gabriel Baonza,Antonio Tagua,Pablo Vicente-Munuera,Ana M. Palacios, María P. Gavilán,Fernando Martín-Belmonte,Valentina Annese,Pedro Gómez-Gálvez,Ignacio Arganda-Carreras,Luis M. Escudero

https://www.biorxiv.org/content/10.1101/2023.01.05.522724v3

preLighter:(default)

writer:(you?)

keywords:Developmental biology, epithelial organisation, segmentation, deep learning-based image analysis

preLight:(not yet highlighted)

manuscript is published:(not yet)

2022

PCP and Septins govern the polarized organization of the actin cytoskeleton during convergent extension

Caitlin C Devitt, Shinuo Weng, Vidal D Bejar-Padilla, José Alvarado, John B Wallingford

https://www.biorxiv.org/content/10.1101/2022.06.06.495000v2

preLighter:(default)

writer:(you?)

keywords:Developmental biology, morphogenesis, planar cell polarity, Septin, actin cytoskeleton, convergent extension,Xenopus

preLight:(not yet highlighted)

manuscript is published:(not yet)

Evolutionary adaptation to juvenile malnutrition impacts adult metabolism and impairs adult fitness inDrosophila

Berra Erkosar, Cindy Dupuis,Fanny Cavigliasso, Loriane Savary, Laurent Kremmer,Hector Gallart-Ayala,Julijana Ivanisevic,Tadeusz J. Kawecki

https://www.biorxiv.org/content/10.1101/2022.01.11.475896v2

preLighter:(default)

writer:(you?)

keywords:Evolutionary biology, experimental evolution, dietary adaptation, Drosophila, metabolome, thrifty phenotype, developmental programming, nutrient restriction, trade-off

preLight:(not yet highlighted)

manuscript is published:(not yet)

Posted on: 29 September 2023 , updated on: 18 October 2023

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